diff --git a/dlls/Maketest.rules.in b/dlls/Maketest.rules.in
index ab059f0c9bb..79e0ac4e0c6 100644
--- a/dlls/Maketest.rules.in
+++ b/dlls/Maketest.rules.in
@@ -9,7 +9,7 @@
 # plus all variables required by the global Make.rules.in
 #
 
-DEFS         = @DLLFLAGS@ -D__WINE__ $(EXTRADEFS)
+DEFS         = @DLLFLAGS@ $(EXTRADEFS)
 LDDLLFLAGS   = @LDDLLFLAGS@
 
 MODULE       = $(TESTDLL:%.dll=%)_test.exe