diff --git a/accel/tcg/cpu-exec.c b/accel/tcg/cpu-exec.c
index 280200f737..9cc697205c 100644
--- a/accel/tcg/cpu-exec.c
+++ b/accel/tcg/cpu-exec.c
@@ -585,6 +585,7 @@ static inline bool cpu_handle_interrupt(CPUState *cpu,
         else {
             if (cc->cpu_exec_interrupt(cpu, interrupt_request)) {
                 replay_interrupt();
+                cpu->exception_index = -1;
                 *last_tb = NULL;
             }
             /* The target hook may have updated the 'cpu->interrupt_request';
@@ -606,7 +607,9 @@ static inline bool cpu_handle_interrupt(CPUState *cpu,
     if (unlikely(atomic_read(&cpu->exit_request)
         || (use_icount && cpu->icount_decr.u16.low + cpu->icount_extra == 0))) {
         atomic_set(&cpu->exit_request, 0);
-        cpu->exception_index = EXCP_INTERRUPT;
+        if (cpu->exception_index == -1) {
+            cpu->exception_index = EXCP_INTERRUPT;
+        }
         return true;
     }