diff --git a/src/cmd/compile/internal/noder/expr.go b/src/cmd/compile/internal/noder/expr.go
index 0e5257d7cf..863acf587d 100644
--- a/src/cmd/compile/internal/noder/expr.go
+++ b/src/cmd/compile/internal/noder/expr.go
@@ -126,13 +126,15 @@ func (g *irgen) expr0(typ types2.Type, expr syntax.Expr) ir.Node {
 				targs[i] = ir.TypeNode(g.typ(inferred.TArgs.At(i)))
 			}
 			if fun.Op() == ir.OFUNCINST {
-				// Replace explicit type args with the full list that
-				// includes the additional inferred type args.
-				// Substitute the type args for the type params in
-				// the generic function's type.
-				fun.(*ir.InstExpr).Targs = targs
-				newt := g.substType(fun.Type(), fun.Type().TParams(), targs)
-				typed(newt, fun)
+				if len(fun.(*ir.InstExpr).Targs) < len(targs) {
+					// Replace explicit type args with the full list that
+					// includes the additional inferred type args.
+					// Substitute the type args for the type params in
+					// the generic function's type.
+					fun.(*ir.InstExpr).Targs = targs
+					newt := g.substType(fun.(*ir.InstExpr).X.Type(), fun.(*ir.InstExpr).X.Type().TParams(), targs)
+					typed(newt, fun)
+				}
 			} else {
 				// Create a function instantiation here, given there
 				// are only inferred type args (e.g. min(5,6), where
diff --git a/test/typeparam/issue48030.go b/test/typeparam/issue48030.go
new file mode 100644
index 0000000000..9fc4428841
--- /dev/null
+++ b/test/typeparam/issue48030.go
@@ -0,0 +1,26 @@
+// run -gcflags=-G=3
+
+// Copyright 2021 The Go Authors. All rights reserved.
+// Use of this source code is governed by a BSD-style
+// license that can be found in the LICENSE file.
+
+package main
+
+type Src[T any] func() Src[T]
+
+func Seq[T any]() Src[T] {
+	return nil
+}
+
+func Seq2[T1 any, T2 any](v1 T1, v2 T2) Src[T2] {
+	return nil
+}
+
+func main() {
+	// Type args fully supplied
+	Seq[int]()
+	// Partial inference of type args
+	Seq2[int](5, "abc")
+	// Full inference of type args
+	Seq2(5, "abc")
+}