diff --git a/benchmarks/AsyncLiveVars/dart/AsyncLiveVars.dart b/benchmarks/AsyncLiveVars/dart/AsyncLiveVars.dart
index 2cd702ccd04..fc28d1be2d8 100644
--- a/benchmarks/AsyncLiveVars/dart/AsyncLiveVars.dart
+++ b/benchmarks/AsyncLiveVars/dart/AsyncLiveVars.dart
@@ -15,27 +15,33 @@ class MockClass {
       List<int>.filled(int.parse('3'), int.parse('42'));
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   String get1() => str;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   List<int> get2() => list;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   void use1(String a0) => a0.length;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   void use2(String a0, List<int> a1) => a0.length + a1.length;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   void use4(String a0, List<int> a1, String a2, List<int> a3) =>
       a0.length + a1.length + a2.length + a3.length;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   void use8(String a0, List<int> a1, String a2, List<int> a3, String a4,
           List<int> a5, String a6, List<int> a7) =>
@@ -49,6 +55,7 @@ class MockClass {
       a7.length;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Future<void> asyncMethod() async {}
 }
@@ -58,26 +65,32 @@ class MockClass2 {
   static int val2 = int.parse('43');
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   int get1() => val1;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   int get2() => val2;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   void use1(int a0) => a0;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   void use2(int a0, int a1) => a0 + a1;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   void use4(int a0, int a1, int a2, int a3) => a0 + a1 + a2 + a3;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Future<void> asyncMethod() async {}
 }
diff --git a/benchmarks/Calls/dart/Calls.dart b/benchmarks/Calls/dart/Calls.dart
index ae546633c91..5715a627b6a 100644
--- a/benchmarks/Calls/dart/Calls.dart
+++ b/benchmarks/Calls/dart/Calls.dart
@@ -103,6 +103,7 @@ Future main() async {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitCallsClosureTargetPolymorphic(
     FutureOr<int> Function(int) fun) async {
@@ -115,6 +116,7 @@ Future<int> performAwaitCallsClosureTargetPolymorphic(
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitAsyncCallsInstanceTargetPolymorphic(
     Target target) async {
@@ -127,6 +129,7 @@ Future<int> performAwaitAsyncCallsInstanceTargetPolymorphic(
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitFutureCallsInstanceTargetPolymorphic(
     Target target) async {
@@ -139,6 +142,7 @@ Future<int> performAwaitFutureCallsInstanceTargetPolymorphic(
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitFutureOrCallsInstanceTargetPolymorphic(
     Target target) async {
@@ -151,6 +155,7 @@ Future<int> performAwaitFutureOrCallsInstanceTargetPolymorphic(
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitAsyncCalls() async {
   int sum = 0;
@@ -162,6 +167,7 @@ Future<int> performAwaitAsyncCalls() async {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitFutureCalls() async {
   int sum = 0;
@@ -173,6 +179,7 @@ Future<int> performAwaitFutureCalls() async {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitFutureOrCalls() async {
   int sum = 0;
@@ -184,6 +191,7 @@ Future<int> performAwaitFutureOrCalls() async {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitAsyncCallsInstanceTargetPolymorphicManyAwaits(
     Target t) async {
@@ -284,6 +292,7 @@ Future<int> performAwaitAsyncCallsInstanceTargetPolymorphicManyAwaits(
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> performAwaitForIterationPolymorphic(
     Stream<int> Function(int) fun) async {
@@ -296,6 +305,7 @@ Future<int> performAwaitForIterationPolymorphic(
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 int performSyncCallsClosureTarget(int Function(int) fun) {
   int sum = 0;
@@ -307,6 +317,7 @@ int performSyncCallsClosureTarget(int Function(int) fun) {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 int performSyncCallsInstanceTargetPolymorphic(Target target) {
   int sum = 0;
@@ -318,6 +329,7 @@ int performSyncCallsInstanceTargetPolymorphic(Target target) {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 int performSyncCalls() {
   int sum = 0;
@@ -329,6 +341,7 @@ int performSyncCalls() {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 int performSyncIterationPolymorphic(Iterable<int> Function(int) fun) {
   int sum = 0;
@@ -340,18 +353,22 @@ int performSyncIterationPolymorphic(Iterable<int> Function(int) fun) {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 FutureOr<int> returnFutureOr(int i) => i;
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> returnFuture(int i) => Future.value(i);
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Future<int> returnAsync(int i) async => i;
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Stream<int> generateNumbersAsyncStar(int limit) async* {
   for (int i = 0; i < limit; ++i) {
@@ -360,6 +377,7 @@ Stream<int> generateNumbersAsyncStar(int limit) async* {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Stream<int> generateNumbersAsyncStar2(int limit) async* {
   for (int i = 0; i < limit; ++i) {
@@ -368,6 +386,7 @@ Stream<int> generateNumbersAsyncStar2(int limit) async* {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Stream<int> generateNumbersManualAsync(int limit) {
   int current = 0;
@@ -395,10 +414,12 @@ Stream<int> generateNumbersManualAsync(int limit) {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 int returnSync(int i) => i;
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Iterable<int> generateNumbersSyncStar(int limit) sync* {
   for (int i = 0; i < limit; ++i) {
@@ -407,6 +428,7 @@ Iterable<int> generateNumbersSyncStar(int limit) sync* {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Iterable<int> generateNumbersSyncStar2(int limit) sync* {
   for (int i = 0; i < limit; ++i) {
@@ -415,11 +437,13 @@ Iterable<int> generateNumbersSyncStar2(int limit) sync* {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Iterable<int> generateNumbersManual(int limit) =>
     Iterable<int>.generate(limit, (int i) => i);
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Iterable<int> generateNumbersSyncStarManyYields(int limit) sync* {
   int i = 0;
@@ -574,6 +598,7 @@ Iterable<int> generateNumbersSyncStarManyYields(int limit) sync* {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Stream<int> generateNumbersAsyncStarManyYields(int limit) async* {
   int i = 0;
@@ -729,18 +754,22 @@ Stream<int> generateNumbersAsyncStarManyYields(int limit) async* {
 
 class Target {
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   FutureOr<int> returnFutureOr(int i) => i;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Future<int> returnFuture(int i) => Future.value(i);
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Future<int> returnAsync(int i) async => i;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   int returnSync(int i) => i;
 }
@@ -748,21 +777,25 @@ class Target {
 class Target2 extends Target {
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   FutureOr<int> returnFutureOr(int i) => i;
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Future<int> returnFuture(int i) => Future.value(i);
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Future<int> returnAsync(int i) async => i;
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   int returnSync(int i) => i;
 }
@@ -770,21 +803,25 @@ class Target2 extends Target {
 class Target3 extends Target {
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   FutureOr<int> returnFutureOr(int i) => i;
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Future<int> returnFuture(int i) => Future.value(i);
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Future<int> returnAsync(int i) async => i;
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   int returnSync(int i) => i;
 }
diff --git a/benchmarks/Dynamic/dart/Dynamic.dart b/benchmarks/Dynamic/dart/Dynamic.dart
index d296f62e7cf..db124796a7c 100644
--- a/benchmarks/Dynamic/dart/Dynamic.dart
+++ b/benchmarks/Dynamic/dart/Dynamic.dart
@@ -50,40 +50,58 @@ void main() {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 void f1(String s) {}
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 Function(String) c1 = (String s) => {};
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 void f2(String s, [String t = 'default']) {}
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 Function(String, [String]) c2 = (String s, [String t = 'default']) => {};
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 void f3(String s, {String t = 'default'}) {}
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 Function(String, {String t}) c3 = (String s, {String t = 'default'}) => {};
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic df1 = f1 as dynamic;
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic dc1 = c1 as dynamic;
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic df2 = f2 as dynamic;
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic dc2 = c2 as dynamic;
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic df3 = f3 as dynamic;
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic dc3 = c3 as dynamic;
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic df1NonCast(dynamic s) {}
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 Function dc1NonCast = (dynamic s) => {};
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic df2NonCast(dynamic s, [dynamic t = 'default']) {}
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 Function dc2NonCast = (dynamic s, [dynamic t = 'default']) => {};
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic df3NonCast(dynamic s, {dynamic t = 'default'}) {}
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 Function dc3NonCast = (dynamic s, {dynamic t = 'default'}) => {};
 
 class A {
@@ -95,6 +113,7 @@ class B extends A {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic k = (A a) {};
 
 class C {
@@ -106,6 +125,7 @@ class D extends C {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 dynamic j = (C c) {};
 
 class NonDynamicFunction extends BenchmarkBase {
diff --git a/benchmarks/InstantiateTypeArgs/dart/InstantiateTypeArgs.dart b/benchmarks/InstantiateTypeArgs/dart/InstantiateTypeArgs.dart
index 91b0794866f..7056ac497b2 100644
--- a/benchmarks/InstantiateTypeArgs/dart/InstantiateTypeArgs.dart
+++ b/benchmarks/InstantiateTypeArgs/dart/InstantiateTypeArgs.dart
@@ -1192,11 +1192,13 @@ class Instantiate1000 extends BenchmarkBase {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 void blackhole<T>() => null;
 
 class D<T> {
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static void instantiate<S>() => blackhole<D<S>>();
 }
diff --git a/benchmarks/InstantiateTypeArgs/generate.dart b/benchmarks/InstantiateTypeArgs/generate.dart
index 643d5afa471..c24766a8f9d 100644
--- a/benchmarks/InstantiateTypeArgs/generate.dart
+++ b/benchmarks/InstantiateTypeArgs/generate.dart
@@ -70,11 +70,13 @@ class Instantiate$count extends BenchmarkBase {
 
   output.write('''
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 void blackhole<T>() => null;
 
 class D<T> {
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static void instantiate<S>() => blackhole<D<S>>();
 }
diff --git a/benchmarks/Iterators/dart/Iterators.dart b/benchmarks/Iterators/dart/Iterators.dart
index d31f0415293..3b9cfc97aff 100644
--- a/benchmarks/Iterators/dart/Iterators.dart
+++ b/benchmarks/Iterators/dart/Iterators.dart
@@ -180,6 +180,7 @@ class PolyBenchmark extends Benchmark {
 /// This function is the inner loop of the benchmark.
 @pragma('dart2js:noInline')
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 void sinkAll(Iterable iterable) {
   for (final value in iterable) {
     sink = value;
diff --git a/benchmarks/MultipleReturns/dart/MultipleReturns.dart b/benchmarks/MultipleReturns/dart/MultipleReturns.dart
index 6b9b15cdcfa..a16ef744307 100644
--- a/benchmarks/MultipleReturns/dart/MultipleReturns.dart
+++ b/benchmarks/MultipleReturns/dart/MultipleReturns.dart
@@ -22,52 +22,64 @@ class ResultClass {
 }
 
 @pragma('vm:prefer-inline')
+@pragma('wasm:prefer-inline')
 @pragma('dart2js:prefer-inline')
 List<Object> inlinedList() => [input1, input2];
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 List<Object> notInlinedList() => [input1, input2];
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 List<Object> forwardedList() => notInlinedList();
 
 @pragma('vm:prefer-inline')
+@pragma('wasm:prefer-inline')
 @pragma('dart2js:prefer-inline')
 ResultClass inlinedClass() => ResultClass(input1, input2);
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 ResultClass notInlinedClass() => ResultClass(input1, input2);
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 ResultClass forwardedClass() => notInlinedClass();
 
 @pragma('vm:prefer-inline')
+@pragma('wasm:prefer-inline')
 @pragma('dart2js:prefer-inline')
 (int, String) inlinedRecord() => (input1, input2);
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 (int, String) notInlinedRecord() => (input1, input2);
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 (int, String) forwardedRecord() => notInlinedRecord();
 
 @pragma('vm:prefer-inline')
+@pragma('wasm:prefer-inline')
 @pragma('dart2js:prefer-inline')
 ({int result0, String result1}) inlinedRecordNamed() =>
     (result0: input1, result1: input2);
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 ({int result0, String result1}) notInlinedRecordNamed() =>
     (result0: input1, result1: input2);
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 ({int result0, String result1}) forwardedRecordNamed() =>
     notInlinedRecordNamed();
diff --git a/benchmarks/RecordCollections/dart/RecordCollections.dart b/benchmarks/RecordCollections/dart/RecordCollections.dart
index 01d5001cc90..0add8527331 100644
--- a/benchmarks/RecordCollections/dart/RecordCollections.dart
+++ b/benchmarks/RecordCollections/dart/RecordCollections.dart
@@ -25,6 +25,7 @@ class Pair {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 List<Object> getPolymorphicListOfClass(
     int length, bool growable, bool withValues) {
@@ -40,6 +41,7 @@ List<Object> getPolymorphicListOfClass(
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 List<Object> getPolymorphicListOfRecords(
     int length, bool growable, bool withValues) {
diff --git a/benchmarks/SubtypeTestCache/dart/SubtypeTestCache.dart b/benchmarks/SubtypeTestCache/dart/SubtypeTestCache.dart
index 40c96473861..054dfc29ada 100644
--- a/benchmarks/SubtypeTestCache/dart/SubtypeTestCache.dart
+++ b/benchmarks/SubtypeTestCache/dart/SubtypeTestCache.dart
@@ -3897,6 +3897,7 @@ class STCSame1000 extends STCBenchmarkBase {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 void check<S>(dynamic s) => s as C<S> Function();
 
diff --git a/benchmarks/SubtypeTestCache/generate.dart b/benchmarks/SubtypeTestCache/generate.dart
index 33013ed6259..b60c1cfea78 100644
--- a/benchmarks/SubtypeTestCache/generate.dart
+++ b/benchmarks/SubtypeTestCache/generate.dart
@@ -111,6 +111,7 @@ class STCSame$maxCount extends STCBenchmarkBase {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:never-inline')
 void check<S>(dynamic s) => s as C<S> Function();
 
diff --git a/benchmarks/TearOff/dart/TearOff.dart b/benchmarks/TearOff/dart/TearOff.dart
index 6fa9bb103b4..545b300f208 100644
--- a/benchmarks/TearOff/dart/TearOff.dart
+++ b/benchmarks/TearOff/dart/TearOff.dart
@@ -13,12 +13,14 @@ class BenchTearOffInlined extends BenchmarkBase {
   int sum = 0;
 
   @pragma('vm:prefer-inline')
+  @pragma('wasm:prefer-inline')
   @pragma('dart2js:prefer-inline')
   void foo(int arg) {
     sum += arg;
   }
 
   @pragma('vm:prefer-inline')
+  @pragma('wasm:prefer-inline')
   @pragma('dart2js:prefer-inline')
   void callIt(void Function(int) func, int arg) {
     func(arg);
@@ -26,6 +28,7 @@ class BenchTearOffInlined extends BenchmarkBase {
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   void run() {
     sum = 0;
@@ -54,12 +57,14 @@ class BenchTearOffInlinedInTry extends BenchmarkBase {
   int sum = 0;
 
   @pragma('vm:prefer-inline')
+  @pragma('wasm:prefer-inline')
   @pragma('dart2js:prefer-inline')
   void foo(int arg) {
     sum += arg;
   }
 
   @pragma('vm:prefer-inline')
+  @pragma('wasm:prefer-inline')
   @pragma('dart2js:prefer-inline')
   void callIt(void Function(int) func, int arg) {
     func(arg);
@@ -67,6 +72,7 @@ class BenchTearOffInlinedInTry extends BenchmarkBase {
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   void run() {
     sum = 0;
@@ -97,12 +103,14 @@ class BenchTearOffNotInlined extends BenchmarkBase {
   int sum = 0;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   void foo(int arg) {
     sum += arg;
   }
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   void callIt(void Function(int) func, int arg) {
     func(arg);
@@ -110,6 +118,7 @@ class BenchTearOffNotInlined extends BenchmarkBase {
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   void run() {
     sum = 0;
@@ -138,12 +147,14 @@ class BenchTearOffNotInlinedInTry extends BenchmarkBase {
   int sum = 0;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   void foo(int arg) {
     sum += arg;
   }
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   void callIt(void Function(int) func, int arg) {
     func(arg);
@@ -151,6 +162,7 @@ class BenchTearOffNotInlinedInTry extends BenchmarkBase {
 
   @override
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   void run() {
     sum = 0;
diff --git a/benchmarks/TypeLiteral/dart/TypeLiteral.dart b/benchmarks/TypeLiteral/dart/TypeLiteral.dart
index fb9f5677bfe..24d8f59d962 100644
--- a/benchmarks/TypeLiteral/dart/TypeLiteral.dart
+++ b/benchmarks/TypeLiteral/dart/TypeLiteral.dart
@@ -125,35 +125,43 @@ void main() {
 }
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Type getT<T>() => T;
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Type getNullableT<T>() => MakeNullable<T?>;
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Type getListOfT<T>() => List<T>;
 
 @pragma('vm:never-inline')
+@pragma('wasm:never-inline')
 @pragma('dart2js:noInline')
 Type getListOfNullableT<T>() => List<T?>;
 
 class Foo<T> {
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Type getT() => T;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Type getNullableT() => MakeNullable<T?>;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Type getListOfT() => List<T>;
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:noInline')
   Type getListOfNullableT() => List<T?>;
 }
diff --git a/benchmarks/TypedDataPoly/dart/TypedDataPoly.dart b/benchmarks/TypedDataPoly/dart/TypedDataPoly.dart
index 4793b866e77..b1a215bdac9 100644
--- a/benchmarks/TypedDataPoly/dart/TypedDataPoly.dart
+++ b/benchmarks/TypedDataPoly/dart/TypedDataPoly.dart
@@ -66,6 +66,7 @@ class Monomorphic extends Base {
   /// can specialize the method according to different sets of input
   /// implementation types.
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static int sum(List<int> list) {
     var s = 0;
@@ -102,6 +103,7 @@ class Baseline extends Base {
         super('TypedDataPoly.baseline', n);
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static int sum(List<int> list) {
     return list.length;
@@ -141,6 +143,7 @@ class Polymorphic1 extends Base {
   }
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static int sum(List<int> list) {
     var s = 0;
@@ -192,6 +195,7 @@ class Polymorphic2 extends Base {
   }
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static int sum(List<int> list) {
     var s = 0;
@@ -235,6 +239,7 @@ class Polymorphic3 extends Base {
   }
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static int sum(List<int> list) {
     var s = 0;
@@ -281,6 +286,7 @@ class Polymorphic4 extends Base {
   }
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static int sum(List<int> list) {
     var s = 0;
@@ -360,6 +366,7 @@ class Polymorphic5 extends Base {
   }
 
   @pragma('vm:never-inline')
+  @pragma('wasm:never-inline')
   @pragma('dart2js:never-inline')
   static int sum(List<int> list) {
     var s = 0;
diff --git a/pkg/dartdev/lib/src/commands/compile.dart b/pkg/dartdev/lib/src/commands/compile.dart
index fbfe061d8b5..9b8fd80ae73 100644
--- a/pkg/dartdev/lib/src/commands/compile.dart
+++ b/pkg/dartdev/lib/src/commands/compile.dart
@@ -545,12 +545,12 @@ class CompileWasmCommand extends CompileSubcommandCommand {
       --closed-world
       --traps-never-happen
       --type-unfinalizing
-      -O3
+      -Os
       --type-ssa
       --gufa
-      -O3
+      -Os
       --type-merging
-      -O1
+      -Os
       --type-finalizing
     '''); // end of binaryenFlags